Understanding Hormone Changes in Your 40s

Medically Reviewed by: Dr. Suzanne Wolf

Feeling a little “off” lately? Low energy, mood swings, sleep disturbances, or changes in metabolism may feel like just stress or aging—but often, they’re linked to shifting hormones. For many women, the 40s mark the start of subtle changes that can affect overall health and well-being.

What’s Happening in Your 40s

As women enter their 40s, the body begins a gradual transition toward perimenopause, the stage before menopause. During this time, levels of key hormones like estrogen, progesterone, and testosterone can fluctuate. These changes can lead to:

• Energy dips and fatigue
• Mood changes or irritability
• Changes in sleep patterns
• Shifts in metabolism and weight distribution
• Hot flashes or night sweats (in some women)

It’s important to remember that every woman experiences these changes differently. Some may notice mild symptoms, while others may feel more pronounced effects.

Why Early Awareness Matters

Proactively monitoring hormone changes can help women manage symptoms and maintain long-term health. Early awareness allows for:

• Targeted testing to understand your hormone levels
• Lifestyle adjustments to support energy, mood, and metabolism
• Personalized guidance from healthcare professionals to address changes before they become disruptive

Simple Steps to Support Hormonal Health

While some hormone shifts are natural, there are actionable ways to support balance and overall wellness:

• Manage stress – Mindfulness, breathing exercises, or gentle movement can help buffer hormone-related mood changes.
• Track symptoms – Keeping a simple journal of sleep, mood, and energy can help identify patterns to discuss with your provider.
• Support brain health – Engage in mentally stimulating activities, like reading, puzzles, or learning new skills, to help maintain cognitive clarity and resileince.

Partnering with a Provider Makes a Difference

Dr. Suzanne Wolf is passionate about supporting women through the perimenopause stage. By understanding the changes your body may be experiencing and discussing options for lifestyle strategies, you can maintain energy, mood, and overall vitality throughout your 40s and beyond.